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To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

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HR proficiency was determined by counting the fraction of GFP-positive cells using a BD LSR II at 56 h post I-SceI transfection

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